“O Vergin Santa” (full title: O Vergin Santa, non m’abbandonare) is a 16th-century Italian lauda spirituali (religious hymn) composed by the Dominican friar and musician Serafino Razzi (1531–1611).
Published in his 1563 Libro primo delle laudi spirituali, this Marian devotional piece is known for its serene, melodic style aimed at encouraging active participation in worship.